ABP-7 (10mg) Peptide

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TB-500 Fragment for Research

Synthetic TB-500 Fragment for Research Use in the United States

ABP-7 (10mg) is a synthetic actin-binding peptide derived from the biologically active domain of Thymosin Beta-4 (Tβ4). This peptide consists of a seven–amino acid sequence (Ac-LKKTETQ) corresponding to residues 17–23 of the parent molecule and is widely recognized as a TB-500 fragment in peptide research.

At Core Peptide, ABP-7 (10mg) is supplied exclusively for laboratory and research use and is intended for customers within the United States seeking high-quality synthetic research peptides.

👉 Learn more about our peptide standards on the
Research Peptides Collection

What Is ABP-7 (10mg)?

It represents the central actin-binding domain of Thymosin Beta-4 and is produced using solid-phase peptide synthesis (SPPS). This domain has been extensively studied for its role in regulating actin polymerization and cytoskeletal dynamics.

Research indicates that ABP-7 interacts with globular actin (G-actin), limiting its conversion into filamentous actin (F-actin). This mechanism, commonly referred to as actin sequestration, makes ABP-7 (10mg) a valuable tool for studying cell migration, cytoskeletal remodeling, and actin-dependent signaling pathways.

What is ABP-7 (10mg) used for in research?
ABP-7 (10mg) is studied in research involving actin dynamics, cytoskeletal remodeling, cell migration, angiogenesis models, and fibrosis-related signaling pathways.

Is ABP-7 (10mg) the same as TB-500?
ABP-7 (10mg) is a fragment of Thymosin Beta-4 and is often referred to as a TB-500 fragment. It represents the central actin-binding domain of the parent molecule.

Is ABP-7 (10mg) legal to purchase in the United States?
Yes. ABP-7 (10mg) may be purchased in the United States for laboratory research purposes only, in accordance with applicable laws and supplier terms.

Is ABP-7 (10mg) intended for human use?
No. ABP-7 (10mg) is strictly intended for laboratory and research use only and is not approved for human or veterinary use.

Chemical Specifications

• Product Name: ABP-7 (10mg)

• Sequence: Ac-LKKTETQ

• Molecular Formula: C₃₈H₈₁N₉O₂₀

• Molecular Weight: 889.5 g/mol

• Peptide Length: 7 amino acids

• Alternate Names: TB-500 Fragment, Thymosin Beta-4 Fragment (17–23)

Research Applications of ABP-7 (10mg)

ABP-7 (10mg) in Wound Healing Research

ABP-7 (10mg) has been studied in preclinical wound repair models, where actin dynamics play a critical role in keratinocyte migration and tissue remodeling. As a functional fragment of Thymosin Beta-4, ABP-7 is often used to investigate cellular behaviors associated with skin repair and epithelial movement in controlled laboratory environments.

ABP-7 (10mg) and Fibrosis Studies

In fibrosis-related research, ABP-7 (10mg) has been evaluated for its interaction with hepatic stellate cell signaling pathways. Studies suggest that the actin-binding domain may influence markers such as α-smooth muscle actin (α-SMA) and collagen type I, making ABP-7 relevant for research focused on fibrotic signaling and cytoskeletal involvement.

ABP-7 (10mg) peptide and Angiogenesis Research

Angiogenesis is highly dependent on endothelial cell migration and actin reorganization. ABP-7 (10mg) has been used in in vitro and ex vivo research models to explore early-stage vascular sprouting and endothelial cell motility, positioning it as a useful peptide for angiogenesis-related laboratory studies.

For additional background on actin biology, visit the
🔗 National Center for Biotechnology Information (NCBI)
and
🔗 PubChem – Thymosin Beta-4

Research Peptides Collection

High-Purity Synthetic Research Peptides Available in the United States

The Research Peptides Collection at Core Peptide features a curated selection of synthetic peptides developed for laboratory and scientific research applications. Our catalog includes well-characterized compounds such as ABP-7 (10mg), TB-500 fragments, and other actin-binding and signaling-related peptides used in cellular and molecular studies.

All peptides offered by Core Peptide are supplied exclusively for research use and are intended for customers within the United States seeking consistent quality, verified synthesis methods, and transparent documentation.

Synthesis and Quality

ABP-7 (10mg) is synthesized using solid-phase peptide synthesis (SPPS) to ensure:

• High sequence accuracy

• Batch-to-batch consistency

• Suitability for laboratory research applications

Explore our synthesis standards here:
👉 Peptide Quality & Manufacturing